Friday, February 15, 2008

Lizard hormone?

i found this article curiously interesting. i had asked my OBGYN, since she had taken me off one diabetes drug that i had been taking for severl months before getting pregnant and put me on a different diabetes kind while pregnant, which will i be on after i have the baby? she said i'd need to contact an endocrinologist after delivery and have them figure it out.
who knows, maybe i'll qualify for this extra amt of lizard hormone. :)

Study being conducted on diabetes drug made with hormone from lizard
Web Posted: 02/15/2008 12:56 AM CST http://www.mysanantonio.com/salife/health/stories/MYSA021408.lizardhormone.kens.c238637a.html
Wendy RigbyKENS 5 Eyewitness News

Controlling his weight is a constant challenge for Alan Weiss, and that's why he's volunteered for a research study of a long-acting version of a drug called Byetta. The original prescription is a twice a day injection, but this newest version is a once-a-week shot. "It's a combination. It supposedly acts directly on the blood sugars. It also helps to lose weight, which is, I think, much more important in controlling my blood sugars," said Weiss. The study is currently in the Phase 3 trial of the once-a-week version of Byetta. The drug could be on the market in two or three years. The key ingredient in the drug is a synthetic hormone found in the saliva of the Gila Monster. In the desert, the large orange and black venomous lizard may eat only three times a year. When the Gila Monster bites its prey, the hormone in the saliva triggers his body to turn on his dormant intestinal tract. Humans have the same hormone in lower doses, but when it's given in a drug form, the hormone helps slow down the intestinal tract, suppress appetite and stimulate the release of insulin. "When they injected this into humans, it does the same thing our natural hormone does, but it's stronger and it lasts longer," said endocrinologist Dr. Sam Miller.
Miller has been testing the once-a-week injection on about 50 patients for a year now, and says the combination of blood sugar control and weight loss is impressive. The weekly shot works in four ways. It signals the pancreas to make the right amount of insulin when you eat. It stops the liver from making too much glucose when you don't need it. It reduces appetite, and it slows down how quickly food and glucose leave the stomach. Miller says the exciting promise of this drug is that some patients may be able to put off the need for insulin and other diabetes medicines as well. "It's quite possible that patients on current medications may, in fact, be able to either reduce their dosage or eliminate them with this medication," said Miller. Weiss has dropped 20 pounds in the past few months and is looking to lose 40 more pounds. He believes this medication is key to his success. "It makes it easier. I'm a bit of a compulsive eater, and it kind of suppresses my appetite most of the time," he said. Type 2 diabetics currently using pills to treat diabetes may qualify to participate in the study. For more information, call (210) 614-4800.

1 comment:

lilricky said...

I would start to worry if you get the unresistable urge to eat insects. ;)